Storm Bella is due to bring gusts of up to 80mph and heavy rain to the UK on Saturday, forecasters have warned.
The Met Office has issued warnings for wind and rain in parts of England, Wales, Northern Ireland and southern Scotland, with coastal areas expected to be impacted the most.
It said 15-25mm of rain is likely to fall in Wales and south-west England, with up to 40-60mm over some hills.
It comes after evacuation centres were set up amid flooding in Bedfordshire.
Residents in 1,300 homes by the River Great Ouse were advised to move out following high water levels on Christmas Day and a “severe” flood warning is in place.
The Met Office’s amber weather warning for parts of Wales and southern England says travel could be disrupted from Saturday night through to Sunday morning.
It also warned that flying debris could cause injury or be a risk to life, and buildings could be damaged in the storm.
Senior meteorologist for DTN Helen Rossington said the north-west of the UK “will bear the brunt” of the heavy rain and strong winds, with gusts of 50 to 60mph.
This could be up to 70mph around some of the islands of western Scotland and the north-west coast of Northern Ireland, she said.
Overnight, gusts could reach up to 80mph for the most exposed coastal areas in the southern parts of England and Wales, she said, with gusts of 45 to 55mph further inland.
“Such gusts are high enough to cause some structural damage, and perhaps bring some trees or branches down, as well as potentially affecting power supplies,” Ms Rossington said.
The highest rain totals will be across western Scotland, where 40-70mm could fall, she added.